Group members

Principle Investigator

Zachary A. Levine

Assistant Professor of Pathology
Yale School of Medicine

PhD, Physics. University of Southern California.
MS, Comp. Sci. University of Southern California.
MA, Physics. University of Southern California.
BS, Physics. San Francisco State University.

Zach obtained his PhD in physics from the University of Southern California in 2013, where he utilized molecular models to study biomembranes and their permeability to external agents and compounds. Building on his work with lipids, Zach was a postdoctoral researcher at the University of California, Santa Barbara where he worked on disordered protein folding in pathological, physiological, and bioengineered systems. He subsequently became an associate research scientist at the Yale School of Medicine in the Departments of Pathology and in Molecular Biophysics & Biochemistry, under the tutelage of Andrew Miranker. In 2019, he was promoted to the rank of Assistant Professor and began integrating theoretical models of disordered protein folding with solution biophysics experiments, which include NMR, ThT spectroscopy, and protein chromatography in amyloidogenic systems. In particular, Zach is interested in soluble amyloid oligomers and their cytotoxicty in human degenerative diseases. These constructs are distinct from insoluble fibrils, which are normally associated with amyloid diseases, and in some instances can undergo in-vivo liquid-liquid phase separation.

Postdoctoral Researchers

Currently recruiting for the Fall '19 Semester!

Graduate Students

Currently recruiting for the Fall '19 Semester!

Undergraduate Students

Currently recruiting for the Fall '19 Semester!